Plan for mathematical model of stem cells in Colorectal Crypt structure

Ouchi, Noriyuki

no journal, , 

To consider biological effects of radiation based on the view point of radiation risk estimation, studying the DNA damage/cellular damage accumulation time scale is very important. Recent years, experimental data suggests that the major target of the radiation is cancer stem cell which is very localized cell within the tissue, elucidation of its dynamics have become an urgent matter. In this presentation, design process of mathematical model to study damage repair timescale (turn-over) is shown for the collaborating with the experiment.